Yale scientists use gene editing to correct mutation in cystic fibrosis
Yale University
New Haven, Conn. – Yale researchers successfully corrected the most common mutation in the gene that causes cystic fibrosis, a lethal genetic disorder. The study was published April 27 in Nature Communications. To correct the mutation, a multidisciplinary team of Yale researchers developed a novel approach. In both human airway cells and mouse nasal cells, the researchers observed corrections in the targeted genes. The technology could be used as a way to fix the basic genetic defect in cystic fibrosis.